Journal of Pharmaceutical and Biomedical Sciences

Significance of Stem Cells in Periodontal Regeneration: An Overview

Rosaiah Kanaparthy, Aruna Kanaparthy, Richa Jain

Abstract


Stem cell refers to a clonogenic, undifferentiated cell that is capable of self-renewal and multi-lineage differentiation. They are unique and form the basis of development, growth and survival of a living organism. Stem cells are the foundation cells of every organ and tissue in the body including the periodontium. Numerous clinical techniques, including bone grafts, root surface conditioning, barrier membranes and various growth factors, have been utilised over the years in an attempt to achieve periodontal regeneration.

The recent identification and isolation of stem cells from the periodontal ligament represents a significant development in the progress towards predictable periodontal regeneration. This review is an overview on the role of stem cells and tissue engineering in periodontal regeneration.


Keywords


Stem cells, periodontal regeneration,tissue engineering

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