Abstract
The aim of this study was to determine outcomes and identify factors that may affect survival in patients with acute invasive fungal rhinosinusitis (AIFRS). Thirty patients of AIFRS were identified. The underlying reasons for immunosuppression were diabetes mellitus (19 patients), chronic renal failure (5 patients), leukemia (3 patients), acquired immunodeficiency syndrome (2 patients) and post organ transplant (1 patient).
We have found the overall survival rate directly related to AIFRS to be 56.7%. The survival rate is higher for young patients (below 50 years age group), diabetic patients than for patients with other causes of immunosuppression, sufferers of mucormycosis than aspergillosis and those treated with liposomal Amphotricsin B as compared to conventional form in addition to surgical debridements. Intracranial and orbital involvement and failure to recover are the factors that led to poor prognosis in this series.
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References
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